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Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF.
Radko-Juettner S, Yue H, Myers JA, Carter RD, Robertson AN, Mittal P, Zhu Z, Hansen BS, Donovan KA, Hunkeler M, Rosikiewicz W, Wu Z, McReynolds MG, Roy Burman SS, Schmoker AM, Mageed N, Brown SA, Mobley RJ, Partridge JF, Stewart EA, Pruett-Miller SM, Nabet B, Peng J, Gray NS, Fischer ES, Roberts CWM. Radko-Juettner S, et al. Among authors: hansen bs. Nature. 2024 Apr;628(8007):442-449. doi: 10.1038/s41586-024-07250-1. Epub 2024 Mar 27. Nature. 2024. PMID: 38538798
Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia.
Chang Y, Min J, Jarusiewicz JA, Actis M, Yu-Chen Bradford S, Mayasundari A, Yang L, Chepyala D, Alcock LJ, Roberts KG, Nithianantham S, Maxwell D, Rowland L, Larsen R, Seth A, Goto H, Imamura T, Akahane K, Hansen BS, Pruett-Miller SM, Paietta EM, Litzow MR, Qu C, Yang JJ, Fischer M, Rankovic Z, Mullighan CG. Chang Y, et al. Among authors: hansen bs. Blood. 2021 Dec 9;138(23):2313-2326. doi: 10.1182/blood.2020006846. Blood. 2021. PMID: 34110416 Free PMC article.
Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection.
Wang Y, Karki R, Zheng M, Kancharana B, Lee S, Kesavardhana S, Hansen BS, Pruett-Miller SM, Kanneganti TD. Wang Y, et al. Among authors: hansen bs. J Immunol. 2021 Nov 15;207(10):2411-2416. doi: 10.4049/jimmunol.2100757. Epub 2021 Oct 18. J Immunol. 2021. PMID: 34663620 Free PMC article.
TERT Expression in Wilms Tumor Is Regulated by Promoter Mutation or Hypermethylation, WT1, and N-MYC.
Jablonowski CM, Gil HJ, Pinto EM, Pichavaram P, Fleming AM, Clay MR, Hu D, Morton CL, Pruett-Miller SM, Hansen BS, Chen X, Jones KMD, Liu Y, Ma X, Yang J, Davidoff AM, Zambetti GP, Murphy AJ. Jablonowski CM, et al. Among authors: hansen bs. Cancers (Basel). 2022 Mar 25;14(7):1655. doi: 10.3390/cancers14071655. Cancers (Basel). 2022. PMID: 35406427 Free PMC article.
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition.
Drosos Y, Myers JA, Xu B, Mathias KM, Beane EC, Radko-Juettner S, Mobley RJ, Larsen ME, Piccioni F, Ma X, Low J, Hansen BS, Peters ST, Bhanu NV, Dhanda SK, Chen T, Upadhyaya SA, Pruett-Miller SM, Root DE, Garcia BA, Partridge JF, Roberts CWM. Drosos Y, et al. Among authors: hansen bs. Mol Cell. 2022 Jul 7;82(13):2472-2489.e8. doi: 10.1016/j.molcel.2022.04.015. Epub 2022 May 9. Mol Cell. 2022. PMID: 35537449 Free PMC article.
Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia.
Ferguson DC, McCorkle JR, Barnett KR, Bonten EJ, Bergeron BP, Bhattarai KR, Yang W, Smith C, Hansen BS, Bajpai R, Dong Q, Autry RJ, Gocho Y, Diedrich JD, Crews KR, Pruett-Miller SM, Roberts KG, Stock W, Mullighan CG, Inaba H, Jeha S, Pui CH, Yang JJ, Relling MV, Evans WE, Savic D. Ferguson DC, et al. Among authors: hansen bs. Blood Adv. 2022 Jun 14;6(11):3386-3397. doi: 10.1182/bloodadvances.2022006965. Blood Adv. 2022. PMID: 35671062 Free PMC article.
Epigenomic profiling of glucocorticoid responses identifies cis-regulatory disruptions impacting steroid resistance in childhood acute lymphoblastic leukemia.
Bergeron BP, Diedrich JD, Zhang Y, Barnett KR, Dong Q, Ferguson DC, Autry RJ, Yang W, Hansen BS, Smith C, Crews KR, Fan Y, Pui CH, Pruett-Miller SM, Relling MV, Yang JJ, Li C, Evans WE, Savic D. Bergeron BP, et al. Among authors: hansen bs. Leukemia. 2022 Oct;36(10):2374-2383. doi: 10.1038/s41375-022-01685-z. Epub 2022 Aug 26. Leukemia. 2022. PMID: 36028659 Free PMC article.
Functional investigation of inherited noncoding genetic variation impacting the pharmacogenomics of childhood acute lymphoblastic leukemia treatment.
Bhattarai KR, Mobley RJ, Barnett KR, Ferguson DC, Hansen BS, Diedrich JD, Bergeron BP, Yang W, Crews KR, Manring CS, Jabbour E, Paietta E, Litzow MR, Kornblau SM, Stock W, Inaba H, Jeha S, Pui CH, Cheng C, Pruett-Miller SM, Relling MV, Yang JJ, Evans WE, Savic D. Bhattarai KR, et al. Among authors: hansen bs. medRxiv [Preprint]. 2023 Feb 11:2023.02.10.23285762. doi: 10.1101/2023.02.10.23285762. medRxiv. 2023. PMID: 36798219 Free PMC article. Updated. Preprint.
133 results