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TRBC1-targeting antibody-drug conjugates for the treatment of T cell cancers.
Nichakawade TD, Ge J, Mog BJ, Lee BS, Pearlman AH, Hwang MS, DiNapoli SR, Wyhs N, Marcou N, Glavaris S, Konig MF, Gabelli SB, Watson E, Sterling C, Wagner-Johnston N, Rozati S, Swinnen L, Fuchs E, Pardoll DM, Gabrielson K, Papadopoulos N, Bettegowda C, Kinzler KW, Zhou S, Sur S, Vogelstein B, Paul S. Nichakawade TD, et al. Among authors: sur s. Nature. 2024 Apr;628(8007):416-423. doi: 10.1038/s41586-024-07233-2. Epub 2024 Mar 27. Nature. 2024. PMID: 38538786
TCR β chain-directed bispecific antibodies for the treatment of T cell cancers.
Paul S, Pearlman AH, Douglass J, Mog BJ, Hsiue EH, Hwang MS, DiNapoli SR, Konig MF, Brown PA, Wright KM, Sur S, Gabelli SB, Li Y, Ghiaur G, Pardoll DM, Papadopoulos N, Bettegowda C, Kinzler KW, Zhou S, Vogelstein B. Paul S, et al. Among authors: sur s. Sci Transl Med. 2021 Mar 10;13(584):eabd3595. doi: 10.1126/scitranslmed.abd3595. Epub 2021 Mar 1. Sci Transl Med. 2021. PMID: 33649188 Free PMC article.
Remote loading of preencapsulated drugs into stealth liposomes.
Sur S, Fries AC, Kinzler KW, Zhou S, Vogelstein B. Sur S, et al. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2283-8. doi: 10.1073/pnas.1324135111. Epub 2014 Jan 28. Proc Natl Acad Sci U S A. 2014. PMID: 24474802 Free PMC article.
An isogenic cell line panel for sequence-based screening of targeted anticancer drugs.
Cook AL, Wyhs N, Sur S, Ptak B, Popoli M, Dobbyn L, Papadopoulos T, Bettegowda C, Papadopoulos N, Vogelstein B, Zhou S, Kinzler KW. Cook AL, et al. Among authors: sur s. iScience. 2022 May 23;25(6):104437. doi: 10.1016/j.isci.2022.104437. eCollection 2022 Jun 17. iScience. 2022. PMID: 35692635 Free PMC article.
Deregulation of energy metabolism promotes antifibrotic effects in human hepatic stellate cells and prevents liver fibrosis in a mouse model.
Karthikeyan S, Potter JJ, Geschwind JF, Sur S, Hamilton JP, Vogelstein B, Kinzler KW, Mezey E, Ganapathy-Kanniappan S. Karthikeyan S, et al. Among authors: sur s. Biochem Biophys Res Commun. 2016 Jan 15;469(3):463-9. doi: 10.1016/j.bbrc.2015.10.101. Epub 2015 Oct 23. Biochem Biophys Res Commun. 2016. PMID: 26525850 Free PMC article.
ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1.
Rincon-Torroella J, Molin MD, Mog B, Han G, Watson E, Wyhs N, Ishiyama S, Ahmedna T, Minn I, Azad NS, Bettegowda C, Papadopoulos N, Kinzler KW, Zhou S, Vogelstein B, Gabrielson K, Sur S. Rincon-Torroella J, et al. Among authors: sur s. bioRxiv [Preprint]. 2023 Jul 25:2023.07.23.550207. doi: 10.1101/2023.07.23.550207. bioRxiv. 2023. PMID: 37546808 Free PMC article. Preprint.
438 results