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115 results

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Intranasal neomycin evokes broad-spectrum antiviral immunity in the upper respiratory tract.
Mao T, Kim J, Peña-Hernández MA, Valle G, Moriyama M, Luyten S, Ott IM, Gomez-Calvo ML, Gehlhausen JR, Baker E, Israelow B, Slade M, Sharma L, Liu W, Ryu C, Korde A, Lee CJ, Silva Monteiro V, Lucas C, Dong H, Yang Y; Yale SARS-CoV-2 Genomic Surveillance Initiative; Gopinath S, Wilen CB, Palm N, Dela Cruz CS, Iwasaki A. Mao T, et al. Among authors: wilen cb. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2319566121. doi: 10.1073/pnas.2319566121. Epub 2024 Apr 22. Proc Natl Acad Sci U S A. 2024. PMID: 38648490 Free PMC article.
A stem-loop RNA RIG-I agonist protects against acute and chronic SARS-CoV-2 infection in mice.
Mao T, Israelow B, Lucas C, Vogels CBF, Gomez-Calvo ML, Fedorova O, Breban MI, Menasche BL, Dong H, Linehan M; Yale SARS-CoV-2 Genome Surveillance Initiative; Wilen CB, Landry ML, Grubaugh ND, Pyle AM, Iwasaki A. Mao T, et al. Among authors: wilen cb. J Exp Med. 2022 Jan 3;219(1):e20211818. doi: 10.1084/jem.20211818. Epub 2021 Nov 10. J Exp Med. 2022. PMID: 34757384 Free PMC article.
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.
Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer RJ, Ring A, Wilen CB, Iwasaki A. Israelow B, et al. Among authors: wilen cb. bioRxiv [Preprint]. 2020 May 27:2020.05.27.118893. doi: 10.1101/2020.05.27.118893. bioRxiv. 2020. PMID: 32577647 Free PMC article. Updated. Preprint.
Restriction of SARS-CoV-2 replication by targeting programmed -1 ribosomal frameshifting.
Sun Y, Abriola L, Niederer RO, Pedersen SF, Alfajaro MM, Silva Monteiro V, Wilen CB, Ho YC, Gilbert WV, Surovtseva YV, Lindenbach BD, Guo JU. Sun Y, et al. Among authors: wilen cb. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2023051118. doi: 10.1073/pnas.2023051118. Proc Natl Acad Sci U S A. 2021. PMID: 34185680 Free PMC article.
Coronavirus Lung Infection Impairs Host Immunity against Secondary Bacterial Infection by Promoting Lysosomal Dysfunction.
Peng X, Kim J, Gupta G, Agaronyan K, Mankowski MC, Korde A, Takyar SS, Shin HJ, Habet V, Voth S, Audia JP, Chang D, Liu X, Wang L, Cai Y, Tian X, Ishibe S, Kang MJ, Compton S, Wilen CB, Dela Cruz CS, Sharma L. Peng X, et al. Among authors: wilen cb. J Immunol. 2022 Oct 1;209(7):1314-1322. doi: 10.4049/jimmunol.2200198. Epub 2022 Sep 2. J Immunol. 2022. PMID: 36165196 Free PMC article.
Simply saliva: stability of SARS-CoV-2 detection negates the need for expensive collection devices.
Ott IM, Strine MS, Watkins AE, Boot M, Kalinich CC, Harden CA, Vogels CBF, Casanovas-Massana A, Moore AJ, Muenker MC, Nakahata M, Tokuyama M, Nelson A, Fournier J, Bermejo S, Campbell M, Datta R; Yale IMPACT Research team; Dela Cruz CS, Farhadian SF, Ko AI, Iwasaki A, Grubaugh ND, Wilen CB, Wyllie AL. Ott IM, et al. Among authors: wilen cb. medRxiv [Preprint]. 2020 Aug 4:2020.08.03.20165233. doi: 10.1101/2020.08.03.20165233. medRxiv. 2020. PMID: 32793924 Free PMC article. Updated. Preprint.
Distinct Roles of Type I and Type III Interferons during a Native Murine β Coronavirus Lung Infection.
Sharma L, Peng X, Qing H, Hilliard BK, Kim J, Swaminathan A, Tian J, Israni-Winger K, Zhang C, Habet V, Wang L, Gupta G, Tian X, Ma Y, Shin HJ, Kim SH, Kang MJ, Ishibe S, Young LH, Kotenko S, Compton S, Wilen CB, Wang A, Dela Cruz CS. Sharma L, et al. Among authors: wilen cb. J Virol. 2022 Jan 26;96(2):e0124121. doi: 10.1128/JVI.01241-21. Epub 2021 Oct 27. J Virol. 2022. PMID: 34705554 Free PMC article.
A humanized mouse model of chronic COVID-19.
Sefik E, Israelow B, Mirza H, Zhao J, Qu R, Kaffe E, Song E, Halene S, Meffre E, Kluger Y, Nussenzweig M, Wilen CB, Iwasaki A, Flavell RA. Sefik E, et al. Among authors: wilen cb. Nat Biotechnol. 2022 Jun;40(6):906-920. doi: 10.1038/s41587-021-01155-4. Epub 2021 Dec 17. Nat Biotechnol. 2022. PMID: 34921308 Free PMC article.
115 results