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373 results

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Page 1
Sedentary behavior in mice induces metabolic inflexibility by suppressing skeletal muscle pyruvate metabolism.
Siripoksup P, Cao G, Cluntun AA, Maschek JA, Pearce Q, Lang MJ, Jeong MY, Eshima H, Ferrara PJ, Opurum PC, Mahmassani ZS, Peterlin AD, Watanabe S, Walsh MA, Taylor EB, Cox JE, Drummond MJ, Rutter J, Funai K. Siripoksup P, et al. Among authors: rutter j. J Clin Invest. 2024 Apr 23;134(11):e167371. doi: 10.1172/JCI167371. Online ahead of print. J Clin Invest. 2024. PMID: 38652544 Free PMC article.
Ceramides Increase Fatty Acid Utilization in Intestinal Progenitors to Enhance Stemness and Increase Tumor Risk.
Li Y, Chaurasia B, Rahman MM, Kaddai V, Maschek JA, Berg JA, Wilkerson JL, Mahmassani ZS, Cox J, Wei P, Meikle PJ, Atkinson D, Wang L, Poss AM, Playdon MC, Tippetts TS, Mousa EM, Nittayaboon K, Anandh Babu PV, Drummond MJ, Clevers H, Shayman JA, Hirabayashi Y, Holland WL, Rutter J, Edgar BA, Summers SA. Li Y, et al. Among authors: rutter j. Gastroenterology. 2023 Nov;165(5):1136-1150. doi: 10.1053/j.gastro.2023.07.017. Epub 2023 Aug 2. Gastroenterology. 2023. PMID: 37541526
Cardiac gene therapy treats diabetic cardiomyopathy and lowers blood glucose.
Li J, Richmond B, Cluntun AA, Bia R, Walsh MA, Shaw K, Symons JD, Franklin S, Rutter J, Funai K, Shaw RM, Hong T. Li J, et al. Among authors: rutter j. JCI Insight. 2023 Sep 22;8(18):e166713. doi: 10.1172/jci.insight.166713. JCI Insight. 2023. PMID: 37639557 Free PMC article.
On the cutting edge: perspectives in bioenergetics.
Granath-Panelo M, Krook A, Rutter J, Kajimura S. Granath-Panelo M, et al. Among authors: rutter j. Nat Rev Endocrinol. 2023 May;19(5):250-251. doi: 10.1038/s41574-023-00820-9. Nat Rev Endocrinol. 2023. PMID: 36869239 Free PMC article.
Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers.
Nussbaum DP, Martz CA, Waters AM, Barrera A, Liu A, Rutter JC, Cerda-Smith CG, Stewart AE, Wu C, Cakir M, Levandowski CB, Kantrowitz DE, McCall SJ, Pierobon M, Petricoin EF 3rd, Joshua Smith J, Reddy TE, Der CJ, Taatjes DJ, Wood KC. Nussbaum DP, et al. Among authors: rutter jc. NPJ Precis Oncol. 2024 May 31;8(1):124. doi: 10.1038/s41698-024-00615-9. NPJ Precis Oncol. 2024. PMID: 38822082
Targeting a lineage-specific PI3Kɣ-Akt signaling module in acute myeloid leukemia using a heterobifunctional degrader molecule.
Kelly LM, Rutter JC, Lin KH, Ling F, Duchmann M, Latour E, Arang N, Pasquer H, Ho Nhat D, Charles J, Killarney ST, Ang HX, Namor F, Culeux C, Lombard B, Loew D, Swaney DL, Krogan NJ, Brunel L, Carretero É, Verdié P, Amblard M, Fodil S, Huynh T, Sebert M, Adès L, Raffoux E, Fenouille N, Itzykson R, Lobry C, Benajiba L, Forget A, Martin AR, Wood KC, Puissant A. Kelly LM, et al. Among authors: rutter jc. Nat Cancer. 2024 May 30. doi: 10.1038/s43018-024-00782-5. Online ahead of print. Nat Cancer. 2024. PMID: 38816660
Lactate transport inhibition therapeutically reprograms fibroblast metabolism in experimental pulmonary fibrosis.
Ziehr DR, Li F, Parnell KM, Krah NM, Leahy KJ, Guillermier C, Varon J, Baron RM, Maron BA, Philp NJ, Hariri LP, Kim EY, Steinhauser ML, Knipe RS, Rutter J, Oldham WM. Ziehr DR, et al. Among authors: rutter j. bioRxiv [Preprint]. 2024 Apr 28:2024.04.25.591150. doi: 10.1101/2024.04.25.591150. bioRxiv. 2024. PMID: 38712233 Free PMC article. Preprint.
373 results