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Page 1
Nanoparticles can cause DNA damage across a cellular barrier.
Bhabra G, Sood A, Fisher B, Cartwright L, Saunders M, Evans WH, Surprenant A, Lopez-Castejon G, Mann S, Davis SA, Hails LA, Ingham E, Verkade P, Lane J, Heesom K, Newson R, Case CP. Bhabra G, et al. Among authors: case cp. Nat Nanotechnol. 2009 Dec;4(12):876-83. doi: 10.1038/nnano.2009.313. Nat Nanotechnol. 2009. PMID: 19893513
Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness.
Sood A, Salih S, Roh D, Lacharme-Lora L, Parry M, Hardiman B, Keehan R, Grummer R, Winterhager E, Gokhale PJ, Andrews PW, Abbott C, Forbes K, Westwood M, Aplin JD, Ingham E, Papageorgiou I, Berry M, Liu J, Dick AD, Garland RJ, Williams N, Singh R, Simon AK, Lewis M, Ham J, Roger L, Baird DM, Crompton LA, Caldwell MA, Swalwell H, Birch-Machin M, Lopez-Castejon G, Randall A, Lin H, Suleiman MS, Evans WH, Newson R, Case CP. Sood A, et al. Among authors: case cp. Nat Nanotechnol. 2011 Nov 6;6(12):824-33. doi: 10.1038/nnano.2011.188. Nat Nanotechnol. 2011. PMID: 22056725
Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions.
Curtis DJ, Sood A, Phillips TJ, Leinster VH, Nishiguchi A, Coyle C, Lacharme-Lora L, Beaumont O, Kemp H, Goodall R, Cornes L, Giugliano M, Barone RA, Matsusaki M, Akashi M, Tanaka HY, Kano M, McGarvey J, Halemani ND, Simon K, Keehan R, Ind W, Masters T, Grant S, Athwal S, Collett G, Tannetta D, Sargent IL, Scull-Brown E, Liu X, Aquilina K, Cohen N, Lane JD, Thoresen M, Hanley J, Randall A, Case CP. Curtis DJ, et al. Among authors: case cp. Exp Neurol. 2014 Nov;261:386-95. doi: 10.1016/j.expneurol.2014.05.003. Epub 2014 May 10. Exp Neurol. 2014. PMID: 24818543
Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development.
Phillips TJ, Scott H, Menassa DA, Bignell AL, Sood A, Morton JS, Akagi T, Azuma K, Rogers MF, Gilmore CE, Inman GJ, Grant S, Chung Y, Aljunaidy MM, Cooke CL, Steinkraus BR, Pocklington A, Logan A, Collett GP, Kemp H, Holmans PA, Murphy MP, Fulga TA, Coney AM, Akashi M, Davidge ST, Case CP. Phillips TJ, et al. Among authors: case cp. Sci Rep. 2017 Aug 22;7(1):9079. doi: 10.1038/s41598-017-06300-1. Sci Rep. 2017. PMID: 28831049 Free PMC article.
Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes.
Hawkins SJ, Crompton LA, Sood A, Saunders M, Boyle NT, Buckley A, Minogue AM, McComish SF, Jiménez-Moreno N, Cordero-Llana O, Stathakos P, Gilmore CE, Kelly S, Lane JD, Case CP, Caldwell MA. Hawkins SJ, et al. Among authors: case cp. Nat Nanotechnol. 2018 May;13(5):427-433. doi: 10.1038/s41565-018-0085-3. Epub 2018 Apr 2. Nat Nanotechnol. 2018. PMID: 29610530
Effects of hTERT on metal ion-induced genomic instability.
Glaviano A, Nayak V, Cabuy E, Baird DM, Yin Z, Newson R, Ladon D, Rubio MA, Slijepcevic P, Lyng F, Mothersill C, Case CP. Glaviano A, et al. Among authors: case cp. Oncogene. 2006 Jun 8;25(24):3424-35. doi: 10.1038/sj.onc.1209399. Epub 2006 Jan 30. Oncogene. 2006. PMID: 16449970
72 results