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Nanoparticles can cause DNA damage across a cellular barrier.
Bhabra G, Sood A, Fisher B, Cartwright L, Saunders M, Evans WH, Surprenant A, Lopez-Castejon G, Mann S, Davis SA, Hails LA, Ingham E, Verkade P, Lane J, Heesom K, Newson R, Case CP. Bhabra G, et al. Among authors: ingham e. Nat Nanotechnol. 2009 Dec;4(12):876-83. doi: 10.1038/nnano.2009.313. Nat Nanotechnol. 2009. PMID: 19893513
Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness.
Sood A, Salih S, Roh D, Lacharme-Lora L, Parry M, Hardiman B, Keehan R, Grummer R, Winterhager E, Gokhale PJ, Andrews PW, Abbott C, Forbes K, Westwood M, Aplin JD, Ingham E, Papageorgiou I, Berry M, Liu J, Dick AD, Garland RJ, Williams N, Singh R, Simon AK, Lewis M, Ham J, Roger L, Baird DM, Crompton LA, Caldwell MA, Swalwell H, Birch-Machin M, Lopez-Castejon G, Randall A, Lin H, Suleiman MS, Evans WH, Newson R, Case CP. Sood A, et al. Among authors: ingham e. Nat Nanotechnol. 2011 Nov 6;6(12):824-33. doi: 10.1038/nnano.2011.188. Nat Nanotechnol. 2011. PMID: 22056725
331 results