United Kingdom Prospective Diabetes Study (UKPDS). Effects of glucose and blood pressure control on complications of type 2 diabetes mellitus

Cleve Clin J Med. 1999 Apr;66(4):247-53. doi: 10.3949/ccjm.66.4.247.

Abstract

The United Kingdom Prospective Diabetes Study (UKPDS) showed that intensive treatment (i.e., glucose-lowering drugs, with a goal fasting blood glucose level of 108 mg/dL) decreases the microvascular complications of type 2 diabetes mellitus. We summarize the key study results and their implications for clinical management of type 2 diabetes mellitus.

MeSH terms

  • Adult
  • Aged
  • Blood Glucose / analysis
  • Blood Pressure
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / metabolism
  • Diabetes Mellitus, Type 2 / prevention & control*
  • Humans
  • Hypertension / complications*
  • Hypertension / prevention & control*
  • Middle Aged
  • Obesity / complications*
  • Obesity / prevention & control*
  • Patient Selection
  • Prospective Studies
  • Treatment Outcome
  • United Kingdom

Substances

  • Blood Glucose