Abstract
Significant advances have been made in determining the genetic basis of the Prader-Willi and Angelman syndromes; disorders in which genomic imprinting is abnormal. These advances will be instrumental in unravelling the pathogenesis that underlies these neurobehavioural disorders.
MeSH terms
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Angelman Syndrome / diagnosis
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Angelman Syndrome / genetics*
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Chromosome Aberrations
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Chromosomes, Human, Pair 15*
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Family Health
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Gene Deletion
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Genomic Imprinting / physiology*
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Humans
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Phenotype
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Prader-Willi Syndrome / diagnosis
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Prader-Willi Syndrome / genetics*
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Risk Assessment