Many headache patients believe that weather changes act as pain triggers. Therefore, the present study investigated the psychophysiological influence of an indicator of atmospheric instability, Very Low Frequency (VLF)-sferics, on 32 subjectively weather-sensitive women suffering from migraine attacks and/or tension-type headaches. It was analyzed if sferics exposure is able to induce electrocortical changes as well as headache symptoms. The subjects, who had been divided into two groups, participated in a sferics simulation study. The experimental group (n = 16) underwent a ten-minute exposure to 10kHz-sferics impulses followed by 20 minutes without treatment in order to examine possible prolonged sferics effects. The control group (n = 16) received no treatment. As dependent measures, EEG spectral power was compared between the two groups at six electrode sites (F3/F4; P3/P4; O1/O2). Sferics exposure provoked increases in absolute alpha and beta power during the treatment. The alpha power enhancement was still present at parietal sites at the end of registration (20 minutes after the end of exposure). The stimulation did not induce headache symptoms.