Striae formation in two HIV-positive persons receiving protease inhibitors

J Am Acad Dermatol. 1999 Sep;41(3 Pt 1):467-9. doi: 10.1016/s0190-9622(99)70122-2.

Abstract

Steroidal side effects such as "buffalo hump" and visceral abdominal fat accumulation have been reported in association with protease inhibitors. We report two cases of severe disfiguring striae formation in patients with HIV who recently started indinavir therapy. These changes occurred within 3 months of starting treatment.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Drug Therapy, Combination
  • Female
  • HIV Protease Inhibitors / adverse effects*
  • HIV Seropositivity / complications*
  • HIV Seropositivity / drug therapy
  • HIV Seropositivity / ethnology
  • HIV Seropositivity / pathology
  • HIV-1 / immunology*
  • Humans
  • Middle Aged
  • Skin / pathology
  • Skin Diseases / chemically induced*
  • Skin Diseases / ethnology
  • Skin Diseases / pathology
  • Uganda / ethnology

Substances

  • HIV Protease Inhibitors