Clinical and molecular features of Ewing sarcoma in a patient with triple-X syndrome

Cancer Genet Cytogenet. 1999 Sep;113(2):188-90. doi: 10.1016/s0165-4608(99)00020-5.

Abstract

A case of Ewing sarcoma in a 16-year-old girl with 47 XXXc karyotype is reported.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Bone Neoplasms / genetics*
  • Bone Neoplasms / secondary
  • Bone Neoplasms / therapy
  • Female
  • Humans
  • Lung Neoplasms / genetics
  • Lung Neoplasms / therapy
  • Male
  • Oncogene Proteins, Fusion / genetics
  • Pregnancy
  • Proto-Oncogene Protein c-fli-1
  • RNA-Binding Protein EWS
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sarcoma, Ewing / genetics*
  • Sarcoma, Ewing / secondary
  • Sarcoma, Ewing / therapy
  • Syndrome
  • Transcription Factors / genetics
  • Trisomy*
  • X Chromosome*

Substances

  • EWS-FLI fusion protein
  • Oncogene Proteins, Fusion
  • Proto-Oncogene Protein c-fli-1
  • RNA-Binding Protein EWS
  • Transcription Factors