Luria's neuropsychology has been particularly influential in the Spanish-speaking world. Its impact is observed with regard to not only assessment, but also rehabilitation, and, especially, neuropsychological theorization. In this article, Luria's approach to neuropsychological assessment is examined. A distinction between Luria's neuropsychological tests and Luria's neuropsychological approach is introduced. It is pointed out that, according to Luria, the specific tests used in the neuropsychological assessment are secondary; the theory supporting the neuropsychological testing is of primary importance. The development of neuropsychology in the Spanish-speaking world is briefly presented, and the use of Luria's neuropsychological assessment procedures in Latin America and Spain is analyzed. Finally, neo-Lurianism in the Spanish-speaking world is considered.