Abstract
Metformin structure and mechanisms of action were presented. Metformin plays a particularly important role in the treatment of diabetes mellitus type 2 by decreasing insulin resistance. Indications of its use include diabetes mellitus type 2 in obese patients without systemic complications or disordered blood supply in large body areas. It may be used as a monotherapy or combined with other oral drugs.
Publication types
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Editorial
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English Abstract
MeSH terms
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Cholesterol, LDL / drug effects
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Diabetes Mellitus, Type 2 / complications
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Diabetes Mellitus, Type 2 / drug therapy*
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Diabetes Mellitus, Type 2 / metabolism
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Humans
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Insulin Resistance*
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Metformin / chemistry
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Metformin / pharmacology
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Metformin / therapeutic use*
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Obesity / complications
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Obesity / metabolism
Substances
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Cholesterol, LDL
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Metformin