Modeling the probability that Ashkenazi Jewish women carry a founder mutation in BRCA1 or BRCA2

Am J Hum Genet. 1999 Dec;65(6):1771-6. doi: 10.1086/302674.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Adult
  • Age of Onset
  • Aging
  • BRCA2 Protein
  • Breast Neoplasms / diagnosis
  • Breast Neoplasms / ethnology
  • Breast Neoplasms / genetics
  • Family Health
  • Female
  • Founder Effect*
  • Genes, BRCA1 / genetics*
  • Heterozygote
  • Humans
  • Jews / genetics*
  • Male
  • Middle Aged
  • Models, Statistical*
  • Mutation / genetics*
  • Neoplasm Proteins / genetics*
  • Ovarian Neoplasms / diagnosis
  • Ovarian Neoplasms / ethnology
  • Ovarian Neoplasms / genetics
  • Penetrance
  • Probability*
  • Transcription Factors / genetics*

Substances

  • BRCA2 Protein
  • Neoplasm Proteins
  • Transcription Factors