Abstract
When synaptic vesicles fuse with the presynaptic plasma membrane, their membrane constituents are recycled by internalisation into clathrin-coated vesicles. To form new synaptic vesicles, the clathrin coat must be shed and recent studies reveal that a lipid phosphatase, synaptojanin, plays a central role in this process.
MeSH terms
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Calcium-Binding Proteins*
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Clathrin / metabolism
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Exocytosis
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Membrane Fusion
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Membrane Glycoproteins / metabolism
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Membrane Lipids / metabolism*
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Nerve Tissue Proteins / metabolism
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Synaptotagmins
Substances
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Calcium-Binding Proteins
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Clathrin
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Membrane Glycoproteins
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Membrane Lipids
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Nerve Tissue Proteins
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Synaptotagmins