Abstract
Human papilloma virus (HPV) is a major risk factor for the development of cervical cancer. As only some infected women develop cancer, other factors must be important for disease development. Genetic epidemiological studies show that genetic factors contribute significantly to disease risk. Genetic susceptibility to HPV exposure and/or infection appears to be important in determining the individual risk to develop this virally induced cancer.
MeSH terms
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Carcinoma in Situ / genetics*
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Carcinoma in Situ / virology
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Female
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Genetic Predisposition to Disease / genetics
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Humans
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Papillomaviridae / physiology*
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Papillomavirus Infections / genetics*
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Papillomavirus Infections / virology
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Risk Factors
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Tumor Virus Infections / genetics*
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Tumor Virus Infections / virology
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Uterine Cervical Dysplasia / genetics*
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Uterine Cervical Dysplasia / virology
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Uterine Cervical Neoplasms / genetics*
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Uterine Cervical Neoplasms / virology