A population-based study of the prevalence, clinical characteristics and effect of ethnicity in epilepsy

Seizure. 2000 Jul;9(5):309-13. doi: 10.1053/seiz.2000.0422.

Abstract

The aim of this study was to determine the prevalence and clinical characteristics of epilepsy and seizure disorders in Bradford. The method used was a community-based cross-sectional study. Case ascertainment was by review of medical records identified by searching practice databases using diagnostic codes and from repeat prescribing data. A specialist epilepsy nurse reviewed the records in 39 practices covering a population of 225 439. Clinical review was undertaken where there was limited information available in the records. In total, 1643 cases of epilepsy were identified (prevalence 7.3/1000). The prevalence of epilepsy increased with age. Classification of patients by internationally agreed definitions showed 1013 (62%) of cases with active epilepsy (prevalence 4. 5/1000); 421 (26%) with epilepsy in remission on treatment and 209 (13%) with epilepsy in remission off treatment. The standardized rate for all patients of South Asian origin was 3.6/1000 compared to 7.8/1000 in the rest of the population (OR 0.46; 95% CI 0.38, 0.57). An underlying aetiology was identified in 29.5% of cases. Cerebrovascular disease and head injuries were the commonest causes.

Conclusions: The prevalence of epilepsy supports previous epidemiological estimates and highlights the public health importance of epilepsy. The low prevalence in the South Asian population is a surprising finding and further research into cultural attitudes to epilepsy and the impact of stigma in the South Asian population in the UK is required.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anticonvulsants / therapeutic use
  • Asia / ethnology
  • Attitude to Health
  • Child
  • Comorbidity
  • Cross-Sectional Studies
  • Drug Prescriptions / statistics & numerical data
  • Epilepsy / drug therapy
  • Epilepsy / epidemiology*
  • Epilepsy / ethnology
  • Epilepsy / etiology
  • Family Practice / statistics & numerical data
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Learning Disabilities / epidemiology*
  • Learning Disabilities / ethnology
  • Male
  • Middle Aged
  • Population Surveillance
  • Prevalence
  • Retrospective Studies
  • United Kingdom / epidemiology

Substances

  • Anticonvulsants