Does massively parallel transcriptome analysis signify the end of cancer histopathology as we know it?

S A Aparicio; C Caldas; B Ponder

doi:10.1186/gb-2000-1-3-reviews1021

Does massively parallel transcriptome analysis signify the end of cancer histopathology as we know it?

Genome Biol. 2000;1(3):REVIEWS1021. doi: 10.1186/gb-2000-1-3-reviews1021. Epub 2000 Sep 15.

Authors

S A Aparicio¹, C Caldas, B Ponder

Affiliation

¹ Department of Oncology, University of Cambridge, Wellcome Trust/MRC Building, Addenbrookes Hospital, Cambridge CB2 2XY,UK. saparici@hgmp.mrc.ac.uk

Abstract

Transcriptional analysis of all the genes expressed by breast tumors has provided the first steps towards defining a molecular signature for the disease, and might ultimately make conventional diagnostic techniques obsolete.

Publication types

Review

MeSH terms

Biomarkers, Tumor / genetics
Breast Neoplasms / classification
Breast Neoplasms / diagnosis
Breast Neoplasms / genetics*
Breast Neoplasms / pathology*
Expressed Sequence Tags
Gene Expression Profiling* / trends
Gene Expression Regulation, Neoplastic
Humans
Neoplasm Staging
Oligonucleotide Array Sequence Analysis / trends
RNA, Neoplasm / analysis
RNA, Neoplasm / genetics

Substances

Biomarkers, Tumor
RNA, Neoplasm