Clinical outcome of patients who develop PAF after CABG surgery

Pacing Clin Electrophysiol. 2001 Feb;24(2):191-3. doi: 10.1046/j.1460-9592.2001.00191.x.

Abstract

This was a retrospective analysis of patients who had CABG surgery at our hospital over a 12-month period to determine the intermediate-term prognosis of those who had developed PAF after their operation before hospital discharge. Of 317 patients who were operated by a single surgical group, 116 (37%) had AF postoperatively of whom 112 had the paroxysmal form. Of these, 36 were treated with class I or III antiarrhythmic drugs and rate control drugs (group 1) and 76 were treated with rate control alone (group 2). Group 3 consisted of 151 randomly selected patients who did not have AF. All patients were reevaluated at 6 weeks to determine their rhythm and clinical status. Only one patient each in groups 1 and 2 was in AF 6 weeks after discharge. There was a trend toward a higher mortality and morbidity in group 2 patients. PAF after coronary surgery appears to be a self-limited disease process. In this cohort of patients, the rate of recurrence of AF after discharge was similar in patients receiving class I or class III antiarrhythmic drugs together with rate control agents compared to those receiving rate control drugs alone.

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use
  • Aged
  • Anti-Arrhythmia Agents / therapeutic use
  • Atrial Fibrillation / drug therapy
  • Atrial Fibrillation / epidemiology*
  • Calcium Channel Blockers / therapeutic use
  • Case-Control Studies
  • Coronary Artery Bypass*
  • Digoxin / therapeutic use
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Morbidity
  • Postoperative Complications / drug therapy
  • Postoperative Complications / epidemiology*
  • Prognosis
  • Random Allocation
  • Recurrence
  • Retrospective Studies
  • Time Factors

Substances

  • Adrenergic beta-Antagonists
  • Anti-Arrhythmia Agents
  • Calcium Channel Blockers
  • Digoxin