Amyloid beta-peptide induces nitric oxide production in rat hippocampus: association with cholinergic dysfunction and amelioration by inducible nitric oxide synthase inhibitors

FASEB J. 2001 Jun;15(8):1407-9. doi: 10.1096/fj.00-0719fje.
No abstract available

MeSH terms

  • Acetylcholine / metabolism*
  • Amyloid beta-Peptides / pharmacology*
  • Animals
  • Cerebral Ventricles
  • Chemotherapy, Cancer, Regional Perfusion
  • Cholinergic Agents
  • Guanidines / pharmacology
  • Hippocampus / drug effects*
  • Hippocampus / metabolism
  • Memory Disorders / prevention & control
  • Microglia / drug effects
  • Models, Biological
  • Nicotine / pharmacology
  • Nitric Oxide / biosynthesis*
  • Nitric Oxide Synthase / antagonists & inhibitors*
  • Nitric Oxide Synthase Type II
  • Peptide Fragments / pharmacology*
  • Rats

Substances

  • Amyloid beta-Peptides
  • Cholinergic Agents
  • Guanidines
  • Peptide Fragments
  • amyloid beta-protein (1-40)
  • Nitric Oxide
  • Nicotine
  • Nitric Oxide Synthase
  • Nitric Oxide Synthase Type II
  • Nos2 protein, rat
  • Acetylcholine
  • pimagedine