Effect of cross-sectional imaging on negative appendectomy and perforation rates in children

Radiology. 2001 Jul;220(1):103-7. doi: 10.1148/radiology.220.1.r01jl17103.

Abstract

Purpose: To compare negative appendectomy and perforation rates in children who underwent ultrasonography (US), computed tomography (CT), or no imaging before urgent appendectomy.

Materials and methods: All children who underwent urgent appendectomy during a 4(1/2)-year period were identified in a surgical billing database. Pathology reports were coded as negative or as showing acute inflammation or perforation. Imaging up to 14 days before appendectomy or abscess drainage was noted, and imaging-based diagnoses were compared with pathologic findings. Patient age and sex were recorded.

Results: Two hundred ninety-nine children, 176 (59%) male and 123 (41%) female (mean age, 10.4 years; age range, 1--21 years), underwent urgent appendectomy. One hundred twenty-six (42%) underwent no imaging, 121 (41%) underwent US with or without CT, and 52 (17%) underwent CT only; 44 (15%) underwent both US and CT. There were significantly higher rates of appendectomy with normal pathologic findings ("negative appendectomy") in patients who underwent no imaging (14% [18 of 126]) or US (17% [20 of 121]) versus the rates in those who underwent CT only (2% [one of 52]) (P =.02 and P =.007, respectively). The negative appendectomy rate was 7% in 96 patients who underwent CT with or without prior US. The perforation rates were not significantly different.

Conclusion: As compared with children who underwent no preoperative imaging and those who underwent US, children who underwent CT had a significantly lower negative appendectomy rate, without a significantly higher perforation rate.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Age Distribution
  • Appendectomy / statistics & numerical data*
  • Appendicitis / diagnostic imaging*
  • Appendicitis / surgery
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Diagnosis, Differential
  • False Negative Reactions
  • False Positive Reactions
  • Female
  • Humans
  • Incidence
  • Intestinal Perforation / diagnostic imaging*
  • Intestinal Perforation / surgery
  • Male
  • Preoperative Care / methods
  • Probability
  • Reference Values
  • Retrospective Studies
  • Risk Factors
  • Rupture, Spontaneous
  • Sensitivity and Specificity
  • Sex Distribution
  • Tomography, X-Ray Computed
  • Ultrasonography
  • Unnecessary Procedures