DNA replication: stable driving prevents fatal smashes

Curr Biol. 2001 Nov 27;11(23):R979-82. doi: 10.1016/s0960-9822(01)00579-6.

Abstract

Cells respond to DNA damage during S phase by slowing chromosome replication. Recent results have shed light on the mechanism by which this 'intra-S phase' checkpoint is implemented.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cell Cycle Proteins / genetics
  • DNA Damage
  • DNA Replication*
  • S Phase*

Substances

  • Cell Cycle Proteins