The role of M cells in Salmonella infection

Microbes Infect. 2001 Nov-Dec;3(14-15):1183-90. doi: 10.1016/s1286-4579(01)01478-2.

Abstract

Intestinal M cells, the specialised antigen-sampling cells of the mucosal immune system, are exploited by Salmonella and other pathogens as a route of invasion. Salmonella entry into M cells and colonisation of Peyer's patches involve mechanisms critical for infection of cultured cells as well as factors not accurately modelled in vitro.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cattle
  • Epithelium / microbiology*
  • Humans
  • Intestinal Mucosa / cytology
  • Intestinal Mucosa / microbiology
  • Mice
  • Peyer's Patches / cytology*
  • Peyer's Patches / microbiology*
  • Salmonella / pathogenicity*
  • Salmonella / physiology
  • Salmonella Infections / microbiology*