Neurosurgical treatment of meningiomas in children and young adults

Childs Nerv Syst. 2001 Dec;17(12):719-23. doi: 10.1007/s00381-001-0516-5. Epub 2001 Nov 16.

Abstract

Object: We studied the frequency, functional outcome, association with neurofibromatosis (NF) and relapse in patients operated on for meningiomas at age 0-20 years in three Norwegian centers between 1972 and 1999.

Methods: Information was collected by examining case notes and histology records, conducting telephone interviews and performing new radiological investigations. Twenty-seven patients were identified. Five had NF, and all 5 developed multiple tumors. In non-NF patients, relapse occurred in 2 out of 19 who underwent total tumor resection, and in all 3 whose surgery was non-radical. There was 1 postsurgical death, and no other major complications. Most patients had few complaints or none at all resulting from their previous tumor or treatment.

Conclusions: Meningiomas without NF have a good prognosis in children and young adults if the tumor can be removed radically. However, relapse can occur many years after the primary operation.

MeSH terms

  • Adolescent
  • Adult
  • Brain / diagnostic imaging
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Infant, Newborn
  • Intracranial Hypertension / etiology
  • Male
  • Meningeal Neoplasms / complications
  • Meningeal Neoplasms / diagnosis
  • Meningeal Neoplasms / surgery*
  • Meningioma / complications
  • Meningioma / diagnosis
  • Meningioma / surgery*
  • Neurofibromatoses / diagnosis
  • Neurofibromatoses / surgery
  • Neurosurgical Procedures / methods
  • Retrospective Studies
  • Tomography, X-Ray Computed