Epidemiological investigation of a food-borne gastroenteritis outbreak caused by Norwalk-like virus in 30 day-care centres

Scand J Infect Dis. 2002;34(2):115-21. doi: 10.1080/00365540110080133.

Abstract

In March 1999, an outbreak of gastroenteritis occurred affecting 30 day-care centres served by the same caterer. A retrospective cohort study was performed in 13 randomly selected day-care centres to determine the source and mode of transmission. Electron microscopy and PCR were used to verify the diagnosis. The overall attack rate (AR) was 37% (195/524): 30% in children and 62% in adults. Modified by the age of the patient, eating pumpkin salad served on 1 March was associated with becoming an early case (odds ratio = 3.9; 95% confidence interval 1.8-8.8). No significant association was found between food consumption and becoming a late case. The primary food-borne AR was 27% and the secondary AR was 14%. The same genotype of Norwalk-like virus was found in 5 cases and in 1 ill and 1 asymptomatic food-handler. Contamination by 1 of the food-handlers seems the most likely route of spread of the virus and underlines the importance of strict hygienic routines.

MeSH terms

  • Adult
  • Caliciviridae Infections / epidemiology*
  • Caliciviridae Infections / virology*
  • Child
  • Child Day Care Centers*
  • Child, Preschool
  • Cohort Studies
  • Cucurbita / virology
  • Disease Outbreaks*
  • Food Handling / standards
  • Food Microbiology*
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / virology*
  • Humans
  • Infant
  • Logistic Models
  • Norovirus / genetics
  • Norovirus / isolation & purification*
  • Norovirus / ultrastructure
  • Polymerase Chain Reaction
  • Retrospective Studies
  • Time Factors