Abstract
Currently, one of the most important unresolved questions concerning Helicobacter pylori is whether eradication of the organism leads to a sustained improvement in symptoms in patients diagnosed with functional (non-ulcer) dyspepsia. Recently, two very similar studies, the ORCHID and OCAY studies, have been completed and the combined results of these two multicentre, multinational, randomised, double blind, controlled clinical trials are reviewed.
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Anti-Bacterial Agents*
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Anti-Ulcer Agents / therapeutic use
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Double-Blind Method
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Drug Therapy, Combination / therapeutic use*
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Dyspepsia / drug therapy
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Dyspepsia / microbiology*
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Helicobacter Infections / complications
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Helicobacter Infections / drug therapy*
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Helicobacter pylori*
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Humans
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Middle Aged
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Multicenter Studies as Topic
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Omeprazole / therapeutic use
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Randomized Controlled Trials as Topic
Substances
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Anti-Bacterial Agents
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Anti-Ulcer Agents
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Omeprazole