Chylous ascites following treatment for gynecologic malignancies

Gynecol Oncol. 2002 Sep;86(3):370-4. doi: 10.1006/gyno.2002.6754.

Abstract

Background: Chylous ascites is a rare complication following abdominal radiation or para-aortic lymph node dissection in the management of gynecologic malignancies. Treatment options include dietary restriction with addition of medium-chain triglycerides, serial paracenteses, total parenteral nutrition, and somatostatin. Current opinion advocates that surgical exploration and peritoneo-venous shunts be reserved for refractory cases.

Cases: Two patients developed chylous ascites, one after completion of surgical staging and chemoradiation for stage IIB squamous carcinoma of the cervix and one following para-aortic lymph node dissection for recurrent malignant mixed mullerian tumor of the endometrium. In both cases resolution of the chylous ascites followed placement of a peritoneo-venous shunt.

Conclusions: Chylous ascites should be considered in the differential diagnosis of ascites in patients with gynecologic malignancy treated with radiation or para-aortic lymph node dissection.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / therapeutic use
  • Cisplatin / adverse effects
  • Cisplatin / therapeutic use
  • Endometrial Neoplasms / surgery*
  • Female
  • Humans
  • Lymph Node Excision / adverse effects
  • Mixed Tumor, Mullerian / surgery*
  • Pericardial Effusion / etiology*
  • Pericardial Effusion / surgery
  • Radiotherapy / adverse effects
  • Uterine Cervical Neoplasms / drug therapy
  • Uterine Cervical Neoplasms / radiotherapy
  • Uterine Cervical Neoplasms / surgery
  • Uterine Cervical Neoplasms / therapy*

Substances

  • Antineoplastic Agents
  • Cisplatin