Association of HLA-DPB1 gene with endometriosis in women of Guangdong Province in China

Di Yi Jun Yi Da Xue Xue Bao. 2002 May;22(5):432-3.

Abstract

Objective: To analyze the hereditary susceptibility in patients with endometriosis by way of genotyping of HLA-DPB1 alleles.

Methods: The allelic types of HLA-DPB1 were detected by sequence-based typing (SBT) in 38 patients with endometriosis and 36 healthy women as the control.

Result: Significant differences in the frequency of HLA-DRB1 allele was not observed between endometriotic patients and normal subjects.

Conclusion: HLA-DPB1 allele may not be related to endometriosis.

MeSH terms

  • Adult
  • Alleles
  • China
  • Endometriosis / genetics*
  • Endometriosis / pathology
  • Female
  • Gene Frequency
  • HLA-DP Antigens / genetics*
  • HLA-DP beta-Chains
  • Humans
  • Middle Aged

Substances

  • HLA-DP Antigens
  • HLA-DP beta-Chains
  • HLA-DPB1 antigen