Abstract
Aim:
To evaluate whether intrauterine growth retardation (IUGR) protects against the development of allergy.
Methods:
A case-control study of 1515 subjects (15-25 y), of whom 430 were cases (birthweight/length below -2 SD for gestational age). Birth data were from the national birth register. The frequencies of allergic diseases were evaluated by questionnaire.
Results:
For the 950 who replied, the frequencies of allergic diseases were similar in cases and controls.
Conclusion:
IUGR does not protect against the development of allergy.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Asthma / epidemiology*
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Asthma / immunology
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Case-Control Studies
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Child Development / physiology
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Confidence Intervals
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Disease Susceptibility / epidemiology*
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Disease Susceptibility / immunology
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Female
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Gestational Age
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Humans
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Hypersensitivity / epidemiology*
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Hypersensitivity / immunology
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Incidence
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Infant, Newborn
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Infant, Small for Gestational Age / immunology*
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Male
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Odds Ratio
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Prognosis
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Reference Values
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Risk Assessment
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Risk Factors
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Sweden / epidemiology