A serotonin uptake-stimulating tetra-peptide found in urines from ADHD children

World J Biol Psychiatry. 2001 Jul;2(3):144-8. doi: 10.3109/15622970109026800.

Abstract

A tetra-peptide has been isolated from the urines of children with Attention Deficit Hyperactivity Disorder (ADHD) that we could not find in control urines. The tetra-peptide (G-S-E-N) stimulates the uptake of serotonin into platelets. The peptide may explain why serotonin is increased in platelets of ADHD children.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Attention Deficit Disorder with Hyperactivity / blood
  • Attention Deficit Disorder with Hyperactivity / urine*
  • Child
  • Child, Preschool
  • Humans
  • Hydrolysis
  • Infant
  • Male
  • Oligopeptides / blood
  • Oligopeptides / urine*
  • Serotonin / blood
  • Serotonin / urine*

Substances

  • Oligopeptides
  • Serotonin