Rapid diagnosis and treatment of mycobacterial keratitis after laser in situ keratomileusis

J Cataract Refract Surg. 2003 May;29(5):1014-8. doi: 10.1016/s0886-3350(02)01613-9.

Abstract

We report the results of laser in situ keratomileusis (LASIK) in a 51-year-old woman with subsequent mycobacterial keratitis diagnosed by staining with acid-fast and fluorochrome methods, a technique known to have good sensitivity and specificity for mycobacteria. A rapid diagnosis was made without waiting for cultures, and treatment was instituted, including tapering of topical steroids and appropriate antibiotic therapy. The result was preservation of the LASIK flap and a favorable visual outcome at 6 months.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amikacin / administration & dosage
  • Bacteriological Techniques
  • Ciprofloxacin / administration & dosage
  • Clarithromycin / administration & dosage
  • Corneal Ulcer / diagnosis*
  • Corneal Ulcer / drug therapy
  • Corneal Ulcer / microbiology
  • Diagnostic Techniques, Ophthalmological
  • Drug Therapy, Combination / administration & dosage
  • Eye Infections, Bacterial / diagnosis*
  • Eye Infections, Bacterial / drug therapy
  • Eye Infections, Bacterial / etiology
  • Female
  • Humans
  • Indicators and Reagents
  • Keratomileusis, Laser In Situ / adverse effects*
  • Middle Aged
  • Mycobacterium Infections, Nontuberculous / diagnosis*
  • Mycobacterium Infections, Nontuberculous / drug therapy
  • Mycobacterium Infections, Nontuberculous / etiology
  • Mycobacterium chelonae / isolation & purification*
  • Myopia / surgery
  • Postoperative Complications*
  • Staining and Labeling / methods
  • Tobramycin / administration & dosage

Substances

  • Indicators and Reagents
  • Ciprofloxacin
  • Amikacin
  • Clarithromycin
  • Tobramycin