Quantum aspects of brain activity and the role of consciousness

Proc Natl Acad Sci U S A. 1992 Dec 1;89(23):11357-61. doi: 10.1073/pnas.89.23.11357.

Abstract

The relationship of brain activity to conscious intentions is considered on the basis of the functional microstructure of the cerebral cortex. Each incoming nerve impulse causes the emission of transmitter molecules by the process of exocytosis. Since exocytosis is a quantal phenomenon of the presynaptic vesicular grid with a probability much less than 1, we present a quantum mechanical model for it based on a tunneling process of the trigger mechanism. Consciousness manifests itself in mental intentions. The consequent voluntary actions become effective by momentary increases of the probability of vesicular emission in the thousands of synapses on each pyramidal cell by quantal selection.

MeSH terms

  • Animals
  • Axons / physiology
  • Axons / ultrastructure
  • Brain / physiology*
  • Cerebral Cortex / physiology
  • Consciousness / physiology*
  • Exocytosis
  • Hippocampus / physiology
  • Humans
  • Models, Theoretical
  • Nerve Endings / anatomy & histology
  • Nerve Endings / physiology
  • Synapses / physiology
  • Synaptic Transmission