Single photon emission tomography assessment of cerebral dopamine D2 receptor blockade in schizophrenia

Biol Psychiatry. 1992 Aug 1;32(3):293-5. doi: 10.1016/0006-3223(92)90111-c.

Authors

D P Geaney¹, P M Ellis, N Soper, B J Shepstone, P J Cowen

Affiliation

¹ University of Oxford Department of Psychiatry, Warneford Hospital, England.

PMID: 1358229
DOI: 10.1016/0006-3223(92)90111-c

No abstract available

MeSH terms

Adult
Aged
Antipsychotic Agents / therapeutic use*
Basal Ganglia / diagnostic imaging
Basal Ganglia / drug effects
Benzamides / pharmacokinetics
Brain / diagnostic imaging
Brain / drug effects*
Cerebellum / diagnostic imaging
Cerebellum / drug effects
Contrast Media
Humans
Iodine Radioisotopes
Male
Middle Aged
Psychiatric Status Rating Scales
Pyrrolidines / pharmacokinetics
Receptors, Dopamine D2 / drug effects*
Schizophrenia / diagnostic imaging
Schizophrenia / drug therapy*
Schizophrenic Psychology*
Tomography, Emission-Computed, Single-Photon*

Substances

Antipsychotic Agents
Benzamides
Contrast Media
Iodine Radioisotopes
Pyrrolidines
Receptors, Dopamine D2
3-iodo-2-hydroxy-6-methoxy-N-((1-ethyl-2-pyrrolidinyl)methyl)benzamide