Prediagnostic human T lymphotropic virus type I provirus loads were highest in Jamaican children who developed seborrheic dermatitis and severe anemia

J Infect Dis. 2004 Jan 1;189(1):41-5. doi: 10.1086/380567. Epub 2003 Dec 31.

Abstract

In a recent clinical analysis of 308 Jamaican children, human T lymphotropic virus type I (HTLV-I) infection was found to be associated with significantly higher incidence rates of seborrheic dermatitis, eczema, and persistent hyperreflexia of the lower limbs and with nonsignificantly increased rates of severe anemia and abnormal lymphocytes. Results of examination of HTLV-I viral markers in the 28 HTLV-I-infected children provided virologic support for the epidemiologic associations of HTLV-I with seborrheic dermatitis and severe anemia in childhood.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anemia / epidemiology
  • Anemia / etiology*
  • Biomarkers / blood
  • Child, Preschool
  • Cohort Studies
  • Comorbidity
  • Dermatitis, Seborrheic / epidemiology
  • Dermatitis, Seborrheic / etiology*
  • Disease Progression
  • HTLV-I Infections / blood
  • HTLV-I Infections / complications*
  • HTLV-I Infections / epidemiology
  • Human T-lymphotropic virus 1 / isolation & purification*
  • Humans
  • Incidence
  • Infant
  • Jamaica / epidemiology
  • Proviruses / isolation & purification*
  • Risk Factors
  • Viral Load

Substances

  • Biomarkers