Behavioral interventions to reduce STD risk in heterosexual women have been developed and tested in randomized, controlled trials. Some interventions have resulted in behavioral changes to reduce STD risk but either did not adequately study or did not affect actual rates of STD acquisition. Two studies have resulted in behavioral and STD rate changes using different intervention techniques (Project SAFE and Project RESPECT). Further studies are underway to improve efficacy and assist transfer to the community. Until interventions are more widely implemented, individual physicians can assist patients by providing a simple STD risk assessment and suggesting alternative behaviors to reduce risk.