Dexamethasone reduces androgen levels in metformin-treated patients with polycystic ovary syndrome

Fertil Steril. 2004 Feb;81(2):459-62. doi: 10.1016/j.fertnstert.2003.06.022.

Abstract

Women with polycystic ovary syndrome treated with metformin and lifestyle advice were studied. Additional treatment with dexamethasone, but not with bromocriptine, further reduced circulating androgen levels.

Publication types

  • Clinical Trial
  • Comparative Study
  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Androgens / blood*
  • Antineoplastic Agents, Hormonal / therapeutic use*
  • Blood Glucose / metabolism
  • Bromocriptine / therapeutic use
  • Dexamethasone / therapeutic use*
  • Double-Blind Method
  • Drug Therapy, Combination
  • Female
  • Humans
  • Hypoglycemic Agents / therapeutic use*
  • Life Style
  • Metformin / therapeutic use*
  • Placebos
  • Polycystic Ovary Syndrome / drug therapy*
  • Sex Hormone-Binding Globulin / metabolism
  • Time Factors

Substances

  • Androgens
  • Antineoplastic Agents, Hormonal
  • Blood Glucose
  • Hypoglycemic Agents
  • Placebos
  • Sex Hormone-Binding Globulin
  • Bromocriptine
  • Dexamethasone
  • Metformin