[Structure and function of nuclear matrix associated regions (S/MARs)]

I P Chernov; S B Akopov; L G Nikolaev

doi:10.1023/b:rubi.0000015767.28683.69

[Structure and function of nuclear matrix associated regions (S/MARs)]

Bioorg Khim. 2004 Jan-Feb;30(1):3-14. doi: 10.1023/b:rubi.0000015767.28683.69.

[Article in Russian]

Authors

I P Chernov¹, S B Akopov, L G Nikolaev

Affiliation

¹ Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, GSP Moscow, 117997 Russia.

PMID: 15040298
DOI: 10.1023/b:rubi.0000015767.28683.69

Abstract

Modern concepts on the chromatin loop-domain organization and the role of the DNA regions specifically binding the nuclear matrix (nuclear scaffold, or S/MARs) in its formation, maintenance, and regulation are discussed. Some S/MAR structural features, properties of binding the nuclear matrix, and probable mechanisms of their involvement in regulation of gene activity are considered. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2004, vol. 30, no. 1; see also http://www.maik.ru.

Publication types

English Abstract
Review

MeSH terms

Amino Acid Sequence
Base Sequence
DNA / chemistry
Molecular Sequence Data
Nuclear Matrix / chemistry*
Nuclear Matrix / physiology*
Structure-Activity Relationship

Substances

DNA