Uniform-sign cross-peak double-quantum-filtered correlation spectroscopy

Leonard J Mueller; Douglas W Elliott; Garett M Leskowitz; Jochem Struppe; Ryan A Olsen; Kee-Chan Kim; Christopher A Reed

doi:10.1016/j.jmr.2004.03.017

Uniform-sign cross-peak double-quantum-filtered correlation spectroscopy

J Magn Reson. 2004 Jun;168(2):327-35. doi: 10.1016/j.jmr.2004.03.017.

Authors

Leonard J Mueller¹, Douglas W Elliott, Garett M Leskowitz, Jochem Struppe, Ryan A Olsen, Kee-Chan Kim, Christopher A Reed

Affiliation

¹ Department of Chemistry, University of California, Riverside, CA 92521, USA. Leonard.Mueller@ucr.edu

PMID: 15140444
DOI: 10.1016/j.jmr.2004.03.017

Abstract

We detail the uniform-sign cross-peak double-quantum-filtered correlation spectroscopy (UC2QF COSY) experiment, a new through-bond correlation method for disordered solids. This experiment is a refocused version of the popular double-quantum-filtered correlation spectroscopy experiment in liquids. Its key feature is that it provides in-phase and doubly absorptive line shapes, which renders it robust for chemical shift correlation in solids. Both theory and experiment point to distinct advantages of this protocol, which are illustrated by several experiments under challenging conditions, including fast magic-angle spinning (30kHz), anisotropic molecular motion, and (13)C correlation spectroscopy at the natural abundance isotope level.