Is immune-mediated complete fetal atrioventricular block reversible by transplacental dexamethasone therapy?

Ultrasound Obstet Gynecol. 2004 Jun;23(6):602-5. doi: 10.1002/uog.1056.

Abstract

We report for the first time a fetal case with sustained regression from isolated complete to first-degree heart block on transplacental treatment with high-dose dexamethasone. Doppler echocardiography is an excellent diagnostic tool in the non-invasive assessment of fetal atrioventricular conduction and its anomalies.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dexamethasone / administration & dosage*
  • Echocardiography, Doppler / methods
  • Female
  • Fetal Blood / physiology
  • Fetal Diseases / diagnostic imaging
  • Fetal Diseases / drug therapy*
  • Fetal Diseases / physiopathology
  • Glucocorticoids / administration & dosage*
  • Heart Block / diagnostic imaging*
  • Heart Block / drug therapy
  • Heart Block / physiopathology
  • Heart Rate, Fetal / physiology
  • Humans
  • Lupus Erythematosus, Systemic / physiopathology
  • Pregnancy
  • Prenatal Care / methods
  • Ultrasonography, Prenatal / methods*

Substances

  • Glucocorticoids
  • Dexamethasone