Concomitant coronary and multiple arch vessel stenoses in patients treated with external beam radiation: pathophysiological basis and endovascular treatment

Catheter Cardiovasc Interv. 2004 Jul;62(3):385-90. doi: 10.1002/ccd.20111.

Abstract

External beam radiation-induced stenoses isolated to the coronary arteries or peripheral vessels have been previously described. We report for the first time the clinical presentation of two patients with concomitant coronary artery and multiple arch vessel disease following external beam radiation of the chest. We review the pathophysiology, discuss the treatment options and describe the percutaneous treatment of coronary, carotid, subclavian, and axillary stenoses related to this rare but likely underdiagnosed disorder.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiography
  • Brachytherapy / adverse effects*
  • Breast Neoplasms / radiotherapy*
  • Carotid Arteries / radiation effects*
  • Carotid Stenosis / etiology*
  • Carotid Stenosis / physiopathology
  • Carotid Stenosis / therapy*
  • Coronary Stenosis / etiology*
  • Coronary Stenosis / physiopathology
  • Coronary Stenosis / therapy*
  • Coronary Vessels / injuries
  • Coronary Vessels / radiation effects*
  • Female
  • Humans
  • Lymphoma, Non-Hodgkin / radiotherapy*
  • Middle Aged