Is rhythm control superior to rate control in patients with atrial fibrillation and congestive heart failure?

Sana M Al-Khatib; Linda K Shaw; Kerry L Lee; Christopher O'Connor; Robert M Califf

doi:10.1016/j.amjcard.2004.06.009

Is rhythm control superior to rate control in patients with atrial fibrillation and congestive heart failure?

Am J Cardiol. 2004 Sep 15;94(6):797-800. doi: 10.1016/j.amjcard.2004.06.009.

Authors

Sana M Al-Khatib¹, Linda K Shaw, Kerry L Lee, Christopher O'Connor, Robert M Califf

Affiliation

¹ Duke Clinical Research Institute, 2400 Pratt Street, PO Box 17969, Durham, NC 27715, USA. alkha001@mc.duke.edu

PMID: 15374794
DOI: 10.1016/j.amjcard.2004.06.009

Abstract

In 1,009 patients with atrial fibrillation and congestive heart failure, the 2-year mortality rate was 31% in patients treated with rate control (n = 505) versus 29% in patients treated with rhythm control (n = 504). After adjusting for differences in baseline characteristics and medications, no significant difference in mortality was found between the 2 groups.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adrenergic beta-Antagonists / therapeutic use
Anti-Arrhythmia Agents / therapeutic use*
Anticoagulants / therapeutic use
Atrial Fibrillation / complications*
Atrial Fibrillation / mortality
Atrial Fibrillation / prevention & control*
Calcium Channel Blockers / therapeutic use
Chi-Square Distribution
Digoxin / therapeutic use
Female
Heart Failure / complications*
Heart Failure / mortality
Humans
Male
Proportional Hazards Models
Statistics, Nonparametric
Treatment Outcome
Warfarin / therapeutic use

Substances

Adrenergic beta-Antagonists
Anti-Arrhythmia Agents
Anticoagulants
Calcium Channel Blockers
Warfarin
Digoxin