Abstract
The second in a series reviewing the HIV/AIDS antiretroviral drugs. This review summarizes the non-protease inhibitor antiretrovirals: nucleoside and nucleotide analogue reverse transcriptase inhibitors (NRTIs), the nonnucleoside reverse transcriptase inhibitors (NNRTIs), and cell membrane fusion inhibitors. In an overview format for primary care physicians and psychiatrists, this review presents the mechanism of action, side effects, toxicities, and drug interactions of these agents.
MeSH terms
-
Acquired Immunodeficiency Syndrome / drug therapy*
-
Adenine / analogs & derivatives*
-
Adenine / therapeutic use
-
Alkynes
-
Anti-Retroviral Agents / pharmacology
-
Anti-Retroviral Agents / therapeutic use*
-
Benzoxazines
-
Cell Membrane Permeability / drug effects
-
Cyclopropanes
-
Delavirdine / therapeutic use
-
Deoxycytidine / analogs & derivatives*
-
Deoxycytidine / therapeutic use
-
Didanosine / therapeutic use
-
Dideoxynucleosides / therapeutic use
-
Drug Interactions*
-
Emtricitabine
-
HIV Fusion Inhibitors / therapeutic use*
-
HIV Seropositivity / drug therapy*
-
Humans
-
Lamivudine / therapeutic use
-
Nevirapine / therapeutic use
-
Organophosphonates / therapeutic use
-
Oxazines / therapeutic use
-
Reverse Transcriptase Inhibitors / pharmacology
-
Reverse Transcriptase Inhibitors / therapeutic use*
-
Stavudine / therapeutic use
-
Tenofovir
-
Zalcitabine / therapeutic use
-
Zidovudine / therapeutic use
Substances
-
Alkynes
-
Anti-Retroviral Agents
-
Benzoxazines
-
Cyclopropanes
-
Dideoxynucleosides
-
HIV Fusion Inhibitors
-
Organophosphonates
-
Oxazines
-
Reverse Transcriptase Inhibitors
-
Deoxycytidine
-
Lamivudine
-
Zidovudine
-
Zalcitabine
-
Nevirapine
-
Tenofovir
-
Stavudine
-
Delavirdine
-
Emtricitabine
-
Adenine
-
efavirenz
-
Didanosine
-
abacavir