Molecular portraits of breast cancer: tumour subtypes as distinct disease entities

Eur J Cancer. 2004 Dec;40(18):2667-75. doi: 10.1016/j.ejca.2004.08.021.

Abstract

This Review describes advances in the characterisation of breast tumour phenotypes using DNA microarrays and the identification of five subtypes of breast cancer with significant clinical implications.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / classification
  • Breast Neoplasms / genetics*
  • Female
  • Gene Expression Regulation, Neoplastic / genetics*
  • Genes, BRCA1*
  • Genes, p53*
  • Humans
  • Oligonucleotide Array Sequence Analysis
  • Phenotype
  • Survival Analysis