Absence of de novo Y-chromosome microdeletions in male children conceived through intracytoplasmic sperm injection

Fertil Steril. 2004 Dec;82(6):1679-80. doi: 10.1016/j.fertnstert.2004.06.039.

Abstract

Molecular screening for Y-chromosome microdeletions in 96 Spanish male children conceived through intracytoplasmic sperm injection (ICSI) was conducted. No microdeletions were detected; these results support the notion that de novo Y-chromosome alterations are rare and unrelated to the ICSI technique itself.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Child
  • Chromosome Deletion*
  • Chromosomes, Human, Y / genetics*
  • Computer Systems
  • Cryptorchidism / genetics
  • Fathers
  • Fertilization*
  • Gene Frequency
  • Genetic Testing*
  • Humans
  • Male
  • Mosaicism
  • Oligospermia / genetics
  • Oligospermia / physiopathology
  • Polymerase Chain Reaction
  • Severity of Illness Index
  • Sperm Injections, Intracytoplasmic* / adverse effects