Prognostic usefulness of white blood cell count and temperature in acute myocardial infarction (from the CARDINAL Trial)

Am J Cardiol. 2005 Mar 1;95(5):614-8. doi: 10.1016/j.amjcard.2004.11.008.

Abstract

White blood cell (WBC) count and temperature are 2 global measures of inflammation that are systematically gathered and easily identifiable in a clinical setting, unlike many other markers of inflammation being investigated in patients with coronary artery disease. The prognostic usefulness of the WBC count and temperature were evaluated in a large acute myocardial infarction trial, the Complement And ReDuction of INfarct size after Angioplasty or Lytics program. Baseline and serial measurements of WBC counts and temperature were correlated with infarct size and clinical outcome.

Publication types

  • Clinical Trial
  • Clinical Trial, Phase II
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Angioplasty
  • Antibodies, Monoclonal / therapeutic use
  • Antibodies, Monoclonal, Humanized
  • Area Under Curve
  • Body Temperature*
  • Chi-Square Distribution
  • Creatine Kinase / blood
  • Humans
  • Leukocyte Count*
  • Linear Models
  • Myocardial Infarction / immunology*
  • Myocardial Infarction / mortality
  • Myocardial Infarction / therapy
  • Predictive Value of Tests
  • Prognosis
  • Single-Chain Antibodies
  • Survival Analysis
  • Thrombolytic Therapy

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Single-Chain Antibodies
  • pexelizumab
  • Creatine Kinase