Abstract
At pH 7.1, saxitoxin decomposes to produce a trace impurity that can interfere with fluorescence sensing when using irradiation wavelengths near 325 nm. The fluorophore acridine is found to be a suitable component of arylmethyl crown ether chemosensors for the fluorescent detection of saxitoxin. These sensors are selective for the detection of saxitoxin over tetrodotoxin.
Publication types
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Comparative Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Biosensing Techniques / methods*
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Chemistry Techniques, Analytical / methods*
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Chromatography, Gel
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Coumarins / chemistry
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Crown Ethers / chemistry*
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Hydrogen-Ion Concentration
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Protein Binding
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Saxitoxin / analysis*
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Saxitoxin / chemistry
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Tetrodotoxin / analysis*
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Tetrodotoxin / chemistry
Substances
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Coumarins
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Crown Ethers
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Saxitoxin
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Tetrodotoxin
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coumarin