Male factor infertility associated with a familial translocation t(1;13)(q24;q10)

Ali Sazci; Nesrin Ercelen; Emel Ergul; Gurler Akpinar

doi:10.1016/j.fertnstert.2004.10.055

Male factor infertility associated with a familial translocation t(1;13)(q24;q10)

Fertil Steril. 2005 May;83(5):1548-50. doi: 10.1016/j.fertnstert.2004.10.055.

Authors

Ali Sazci¹, Nesrin Ercelen, Emel Ergul, Gurler Akpinar

Affiliation

¹ Department of Medical Biology and Genetics, Faculty of Medicine, University of Kocaeli, Derince, Turkey. alisazci@superonline.com

PMID: 15866603
DOI: 10.1016/j.fertnstert.2004.10.055

Abstract

We report a case of a family with one sister and one brother in which the brother inherited a t(1;13)(q24;q10) translocation from his mother. We describe a case with a clear translocation between the long arm of chromosome 1 and the long arm of chromosome 13. It is possible that the APOE and MTHFR genotypes and lower folate status may also be responsible for the above mentioned translocation.

Publication types

Case Reports

MeSH terms

Adult
Chromosomes, Human, Pair 1 / genetics*
Chromosomes, Human, Pair 13 / genetics*
Female
Humans
Infertility, Male / genetics*
Male
Pedigree
Translocation, Genetic / genetics*