Isolated central nervous system involvement in adult T-cell lymphoma/leukaemia

Br J Haematol. 2005 Aug;130(4):511-5. doi: 10.1111/j.1365-2141.2005.05629.x.

Abstract

Central nervous system (CNS) presentation of adult T-cell lymphoma/leukaemia is rare, and almost invariably associated with systemic disease. We report an unusual manifestation of adult T-cell lymphoma/leukaemia, with isolated CNS involvement and unusual imaging findings. We also describe objective response to antiviral therapy. To our knowledge, this is the first report of such presentation and response.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Antiviral Agents / therapeutic use
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / surgery
  • Brain Neoplasms / therapy
  • Disease Progression
  • Frontal Lobe / surgery
  • Humans
  • Interferons / therapeutic use
  • Leukemia-Lymphoma, Adult T-Cell / diagnosis*
  • Leukemia-Lymphoma, Adult T-Cell / surgery
  • Leukemia-Lymphoma, Adult T-Cell / therapy
  • Magnetic Resonance Imaging
  • Male
  • Palliative Care
  • Tomography, X-Ray Computed

Substances

  • Antiviral Agents
  • Interferons