[Comparative study between the therapeutic effects of surgical myocardial revascularization and coronary angioplasty in equivalent ischemic situations: analysis through myocardial scintigraphy with 99mTc-Sestamibi]

Arq Bras Cardiol. 2005 Aug;85(2):92-9. doi: 10.1590/s0066-782x2005001500004. Epub 2005 Aug 18.
[Article in Portuguese]

Abstract

Objective: To assess the myocardial ischemic load to previous and after myocardial revascularization.

Methods: Ninety-six randomized patients, carriers of multivessel coronary artery disease, stable angina, preserved left ventricular function, and exercise-induced myocardial ischemia treated with revascularization (SMR) or coronary angioplasty (TCA). Myocardial scintigraphy with 99mTc-Sestamibi was performed prior to and 6 months after myocardial revascularization.

Results: The SMR determined a significant greater index of complete revascularization (p=0.001), an increase in the number of maximum ergometric tests (p=0.001) and reduction in the number of positive ergometric tests with exercise angina (p=0.018). Both procedures provided an important improvement in the functional class of angina (p=0.001), an increase in the average value of double peak product (p=0.009), and the time of exercise tolerance (p<0.001), besides the reduction in the average value of the summed of exercise score (p<0.001) and the difference of the summed of scores (p<0.001) in both groups.

Conclusion: TCA and SMR did not differ significantly concerning the reduction of myocardial ischemic load 6 months after the procedure. The myocardial revascularization was more complete with the SMR than the TCA, but it did not represent a significant factor for the reduction myocardial ischemic load.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Angina Pectoris / classification
  • Angina Pectoris / diagnostic imaging
  • Angina Pectoris / therapy
  • Angioplasty, Balloon, Coronary
  • Coronary Vessels / diagnostic imaging*
  • Exercise Test
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Ischemia / diagnostic imaging*
  • Myocardial Ischemia / surgery
  • Myocardial Ischemia / therapy*
  • Myocardial Revascularization / methods*
  • Prospective Studies
  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi
  • Tomography, Emission-Computed, Single-Photon
  • Treatment Outcome

Substances

  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi