Regular abdominal pain and fever in each menstruation onset: an unusual menses-associated familial Mediterrenean fever attacks and a favor result on colchicine treatment

Rheumatol Int. 2006 Jun;26(8):760-1. doi: 10.1007/s00296-005-0055-6. Epub 2005 Sep 23.

Abstract

We present a 38-year-old woman suffering from regular abdominal pain and fever only in each menstruation onset for 7 years. The clinical symptoms, along with inflammatory findings during painful attacks, the beneficial effect of colchicine and genetic mutation (M694 V and M680I) supported the diagnosis of familial Mediterranean fever (FMF). A literature review indicated that FMF attacks occurring only during menstruation are rarely seen. This clinical picture may be confused with gynecological disorders especially in the people of Mediterranean origin.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain / etiology*
  • Adult
  • Colchicine / therapeutic use*
  • Familial Mediterranean Fever / complications
  • Familial Mediterranean Fever / diagnosis*
  • Familial Mediterranean Fever / drug therapy*
  • Familial Mediterranean Fever / genetics
  • Female
  • Fever / etiology*
  • Follow-Up Studies
  • Gout Suppressants / therapeutic use*
  • Humans
  • Menstruation Disturbances / complications
  • Menstruation Disturbances / genetics*
  • Time Factors
  • Treatment Outcome

Substances

  • Gout Suppressants
  • Colchicine